Human induced pluripotent stem cells can generate pre-epicardial cells (PEC) that can stimulate heart cell growth, spatially organize them in the dish and improve their contractility.

The mechanism underlying the increased heart cell proliferation is partly by the retinoic acid / insulin- like growth factor mediated signaling. The collective effects from PEC on heart cells shows their important role especially in heart tissue engineering for regenerative purposes.

2021

Paper published in Nature Communication with Prof. Harald Ott from Harvard University, USA

Nature Communications

• To investigate the role of polymer that impregnated into resin on the interaction mechanism of polymer and two different protein species, bacteriocin and lipase by measuring partition coefficient.
• To investigate the extraction behaviors of two different protein species, bacteriocin and lipase, to focus on impregnation in terms of stability and phase system via protein-impregnated resin interactions in TAPPIR system.
• To show the effect of extraction process parameters of TAPPIR system on two different proteins, bacteriocin and lipase, using response surface methodology and artificial neural network for enhancement of the performance of TAPPIR system in combination with flotation system.

Impact To Goverment / Industry / Academic / Society

Tunable Aqueous Polymer-Phase Impregnated Resins Technology

Impregnation of dyed PEG into XAD4 resins

Recovery of bovine serum albumin (BSA) using AIRS

Polymer phase impregnation and extraction behavior of protein

• To characterize the thin-coated adsorbent layer.
• To study the adsorption interaction of thin-coated adsorbent layer with adsorbent.
• To analyse thin-coated adsorbent layer with adsorbent.

Impact To Goverment / Industry / Academic / Society

FRGS create opportunities for researchers to scientifically discover a fundamental concept. For example, this research leads to the development of a special formulated paint, works as thin-coated adsorbent layer with novelty in its application. This product contributes to an affordable and effective treatment of contaminated industrial effluent. It is highly potential for commercialization, which will start a new wealth creation for Malaysian. Besides driving the nations towards sustainability by applying this product for relevant industries.

• To investigate the effect of surface functionalizing agents (DMDEOS and SA) concentration, drying time, temperature on the surface free energy and roughness of the micro- structure.
• To investigate the bonding interactions between DMDEOS, SA and paper waste ash which affect the strength and durability.
• To examine the fundamental growth mechanism involved in the formation of super-hydrophobic surface using POFA waste, SA and DMDEOS.

Impact To Goverment / Industry / Academic / Society